The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

Mutations in rhodopsin, the light-sensitive protein of rod cells, are the most common cause of autosomal dominant retinitis pigmentosa (ADRP). Many rod opsin mutations, such as P23H, lead to misfolding of rod opsin with detrimental effects on photoreceptor function and viability. Misfolded P23H rod...

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Detalles Bibliográficos
Autores principales: Athanasiou, Dimitra, Bevilacqua, Dalila, Aguila, Monica, McCulley, Caroline, Kanuga, Naheed, Iwawaki, Takao, Paul Chapple, J., Cheetham, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240209/
https://www.ncbi.nlm.nih.gov/pubmed/25055872
http://dx.doi.org/10.1093/hmg/ddu385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240209/
https://www.ncbi.nlm.nih.gov/pubmed/25055872
http://dx.doi.org/10.1093/hmg/ddu385

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