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Improved performance of sequence search approaches in remote homology detection
The protein sequence space is vast and diverse, spanning across different families. Biologically meaningful relationships exist between proteins at superfamily level. However, it is highly challenging to establish convincing relationships at the superfamily level by means of simple sequence searches...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240247/ https://www.ncbi.nlm.nih.gov/pubmed/25469226 http://dx.doi.org/10.12688/f1000research.2-93.v2 |