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Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease models

Rhipicephalus sanguineus, the common brown dog tick, produces several chemokine-binding proteins which are secreted into the host in its saliva to modulate the host response during feeding. Two of these demonstrate very restricted selectivity profiles. Here, we describe the characterization of the t...

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Detalles Bibliográficos
Autores principales: Déruaz, Maud, Bonvin, Pauline, Severin, India C, Johnson, Zoë, Krohn, Sonja, Power, Christine A, Proudfoot, Amanda E I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240464/
https://www.ncbi.nlm.nih.gov/pubmed/23910450
http://dx.doi.org/10.1111/febs.12463