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Promoter trapping method: transcription factor purification using human telomerase reverse transcriptase promoter

BACKGROUND: Transcription factors bind to response elements on the promoter regions of genes to regulate transcriptional activity. One of the major problems with identifying transcription factors is their low abundance relative to other proteins in the cell. Developing a purification technique speci...

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Detalles Bibliográficos
Autores principales: Nagore, Linda I, Zhou, YanWen, Nadeau, Robert J, Jia, YinShan, Jarrett, Harry W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240814/
https://www.ncbi.nlm.nih.gov/pubmed/25425973
http://dx.doi.org/10.1186/s12953-014-0053-2