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Promoter trapping method: transcription factor purification using human telomerase reverse transcriptase promoter
BACKGROUND: Transcription factors bind to response elements on the promoter regions of genes to regulate transcriptional activity. One of the major problems with identifying transcription factors is their low abundance relative to other proteins in the cell. Developing a purification technique speci...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240814/ https://www.ncbi.nlm.nih.gov/pubmed/25425973 http://dx.doi.org/10.1186/s12953-014-0053-2 |