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The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases

BACKGROUND: The extracellular domains of cytokine receptors are released during inflammation, but little is known about the shedding of Toll-like receptors (TLR) and whether they can be used as diagnostic biomarkers. METHODS: The release of sTLR2 and sTLR4 was studied in in-vitro stimulations, as we...

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Detalles Bibliográficos
Autores principales: ten Oever, Jaap, Kox, Matthijs, van de Veerdonk, Frank L, Mothapo, Khutso M, Slavcovici, Adriana, Jansen, Tim L, Tweehuysen, Lieke, Giamarellos-Bourboulis, Evangelos J, Schneeberger, Peter M, Wever, Peter C, Stoffels, Monique, Simon, Anna, van der Meer, Jos WM, Johnson, Melissa D, Kullberg, Bart-Jan, Pickkers, Peter, Pachot, Alexandre, Joosten, Leo AB, Netea, Mihai G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240815/
https://www.ncbi.nlm.nih.gov/pubmed/25406630
http://dx.doi.org/10.1186/s12865-014-0055-y