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Non-small cell lung cancer with EML4-ALK translocation in Chinese male never-smokers is characterized with early-onset

BACKGROUND: The translocations of the anaplastic lymphoma kinase (ALK) gene with the echinoderm microtubule-associated protein-like 4 (EML4) gene on chromosome 2p have been identified in non-small-cell lung cancers (NSCLCs) as oncogenic driver mutations. It has been suggested that EML4-ALK fusion is...

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Detalles Bibliográficos
Autores principales: Guo, Yongjun, Ma, Jie, Lyu, Xiaodong, Liu, Hai, Wei, Bing, Zhao, Jiuzhou, Fu, Shuang, Ding, Lu, Zhang, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240865/
https://www.ncbi.nlm.nih.gov/pubmed/25407901
http://dx.doi.org/10.1186/1471-2407-14-834