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Neurogenin 3–Directed Cre Deletion of Tsc1 Gene Causes Pancreatic Acinar Carcinoma()()

The role of tuberous sclerosis complex (TSC) in the pathogenesis of pancreatic cancers remains largely unknown. The present study shows that neurogenin 3 directed Cre deletion of Tsc1 gene induces the development of pancreatic acinar carcinoma. By cross-breeding the Neurog3-cre mice with Tsc1(loxp/l...

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Detalles Bibliográficos
Autores principales: Ding, Li, Han, Lingling, Li, Yin, Zhao, Jing, He, Ping, Zhang, Weizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240920/
https://www.ncbi.nlm.nih.gov/pubmed/25425965
http://dx.doi.org/10.1016/j.neo.2014.08.010