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Clinicopathological Significance of ATM-Chk2 Expression in Sporadic Breast Cancers: a Comprehensive Analysis in Large Cohorts()

ATM-Chk2 network is critical for genomic stability, and its deregulation may influence breast cancer pathogenesis. We investigated ATM and Chk2 protein levels in two cohorts [cohort 1 (n = 1650) and cohort 2 (n = 252)]. ATM and Chk2 mRNA expression was evaluated in the Molecular Taxonomy of Breast C...

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Detalles Bibliográficos
Autores principales: Abdel-Fatah, Tarek M.A., Arora, Arvind, Alsubhi, Nouf, Agarwal, Devika, Moseley, Paul M., Perry, Christina, Doherty, Rachel, Chan, Stephen Y.T., Green, Andrew R., Rakha, Emad, Ball, Graham, Ellis, Ian O., Madhusudan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240925/
https://www.ncbi.nlm.nih.gov/pubmed/25425972
http://dx.doi.org/10.1016/j.neo.2014.09.009