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A theoretical examination of the relative importance of evolution management and drug development for managing resistance

Drug resistance is a serious public health problem that threatens to thwart our ability to treat many infectious diseases. Repeatedly, the introduction of new drugs has been followed by the evolution of resistance. In principle, there are two complementary ways to address this problem: (i) enhancing...

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Detalles Bibliográficos
Autores principales: McClure, Nathan S., Day, Troy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240990/
https://www.ncbi.nlm.nih.gov/pubmed/25377456
http://dx.doi.org/10.1098/rspb.2014.1861