Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson’s syndrome

The study of mutations causing the steroid-resistant nephrotic syndrome in children has greatly advanced our understanding of the kidney filtration barrier. In particular, these genetic variants have illuminated the roles of the podocyte, glomerular basement membrane and endothelial cell in glomerul...

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Detalles Bibliográficos
Autores principales: Bull, Katherine R, Mason, Thomas, Rimmer, Andrew J, Crockford, Tanya L, Silver, Karlee L, Bouriez-Jones, Tiphaine, Hough, Tertius A, Chaudhry, Shirine, Roberts, Ian SD, Goodnow, Christopher C, Cornall, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2013
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241031/
https://www.ncbi.nlm.nih.gov/pubmed/24293254
http://dx.doi.org/10.1002/path.4308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241031/
https://www.ncbi.nlm.nih.gov/pubmed/24293254
http://dx.doi.org/10.1002/path.4308

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