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Exenatide can inhibit calcification of human VSMCs through the NF-kappaB/RANKL signaling pathway
BACKGROUND: Arterial calcification is an important pathological change of diabetic vascular complication. Osteoblastic differentiation of vascular smooth muscle cells (VSMCs) plays an important cytopathologic role in arterial calcification. The glucagon-like peptide-1 receptor agonists (GLP-1RA), a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241215/ https://www.ncbi.nlm.nih.gov/pubmed/25407893 http://dx.doi.org/10.1186/s12933-014-0153-4 |