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Exenatide can inhibit calcification of human VSMCs through the NF-kappaB/RANKL signaling pathway

BACKGROUND: Arterial calcification is an important pathological change of diabetic vascular complication. Osteoblastic differentiation of vascular smooth muscle cells (VSMCs) plays an important cytopathologic role in arterial calcification. The glucagon-like peptide-1 receptor agonists (GLP-1RA), a...

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Detalles Bibliográficos
Autores principales: Zhan, Jun-Kun, Tan, Pan, Wang, Yan-Jiao, Wang, Yi, He, Jie-Yu, Tang, Zhi-Yong, Huang, Wu, Liu, You-Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241215/
https://www.ncbi.nlm.nih.gov/pubmed/25407893
http://dx.doi.org/10.1186/s12933-014-0153-4