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Parameter estimation of dynamic biological network models using integrated fluxes

BACKGROUND: Parameter estimation is often the bottlenecking step in biological system modeling. For ordinary differential equation (ODE) models, the challenge in this estimation has been attributed to not only the lack of parameter identifiability, but also computational issues such as finding globa...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241227/
https://www.ncbi.nlm.nih.gov/pubmed/25403239
http://dx.doi.org/10.1186/s12918-014-0127-x