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Parameter estimation of dynamic biological network models using integrated fluxes
BACKGROUND: Parameter estimation is often the bottlenecking step in biological system modeling. For ordinary differential equation (ODE) models, the challenge in this estimation has been attributed to not only the lack of parameter identifiability, but also computational issues such as finding globa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241227/ https://www.ncbi.nlm.nih.gov/pubmed/25403239 http://dx.doi.org/10.1186/s12918-014-0127-x |