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Heterogeneous Red Blood Cell Adhesion and Deformability in Sickle Cell Disease
We present a microfluidic approach that allows simultaneous interrogation of RBC properties in physiological flow conditions at a single cell level. With this method, we studied healthy hemoglobin A (HbA) and homozygous sickle hemoglobin (HbS) containing RBCs using whole blood samples from twelve su...
Autores principales: | Alapan, Yunus, Little, Jane A., Gurkan, Umut A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241514/ https://www.ncbi.nlm.nih.gov/pubmed/25417696 http://dx.doi.org/10.1038/srep07173 |
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