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Heterogeneous Red Blood Cell Adhesion and Deformability in Sickle Cell Disease

We present a microfluidic approach that allows simultaneous interrogation of RBC properties in physiological flow conditions at a single cell level. With this method, we studied healthy hemoglobin A (HbA) and homozygous sickle hemoglobin (HbS) containing RBCs using whole blood samples from twelve su...

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Detalles Bibliográficos
Autores principales: Alapan, Yunus, Little, Jane A., Gurkan, Umut A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241514/
https://www.ncbi.nlm.nih.gov/pubmed/25417696
http://dx.doi.org/10.1038/srep07173