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Effects of rosuvastatin on ADMA, rhokinase, NADPH oxidase, caveolin-1, hsp 90 and NFkB levels in a rat model of myocardial ischaemia–reperfusion

AIM: Endothelial dysfunction, oxidative stress and inflammation are among the most important mechanisms of ischaemia–reperfusion (I/R) injury. Besides their cholesterol-lowering effects, statins are known to provide protection against myocardial dysfunction and vascular endothelial injury via nitric...

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Detalles Bibliográficos
Autores principales: Burma, Oktay, Uysal, Ayhan, Onat, Elif, Sahna, Engin, Ilhan, Necip, Erol, Deniz, Ozcan, Mete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241597/
https://www.ncbi.nlm.nih.gov/pubmed/25629537
http://dx.doi.org/10.5830/CVJA-2014-038