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Formulation and characterization of hydrochlorothiazide solid lipid microparticles based on lipid matrices of Irvingia fat

INTRODUCTION: The purpose of this study was to improve the solubilization, bioavailability, and permeability of hydrochlorothiazide (HCTZ) by the formulation and characterization of HCTZ solid lipid microparticles (SLMs) based on fat derived from Irvingia gabonensis var. excelsa (Irvingia wombolu) a...

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Detalles Bibliográficos
Autores principales: Agubata, Chukwuma O., Chime, Salome A., Kenechukwu, Franklin C., Nzekwe, Ifeanyi T., Onunkwo, Godswill C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241624/
https://www.ncbi.nlm.nih.gov/pubmed/25426440
http://dx.doi.org/10.4103/2230-973X.143120