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Formulation Development and evaluation of fast disintegrating tablets of Lamotrigine using liqui-solid technique

INTRODUCTION: Epilepsy is a serious neurological disorder. Lamotrigine is an alternative to lithium for the treatment of epilepsy, and its oral bioavailability is 98%; however, its poor aqueous solubility hinders its oral absorption. Among the techniques available to enhance the solubility, dissolut...

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Detalles Bibliográficos
Autores principales: Koteswari, Poluri, Sunium, Suvarnala, Srinivasababu, Puttugunta, Babu, Govada Kishore, Nithya, Pinnamraju Durga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241626/
https://www.ncbi.nlm.nih.gov/pubmed/25426442
http://dx.doi.org/10.4103/2230-973X.143125