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Anti-CD20 inhibits T cell-mediated pathology and microgliosis in the rat brain
OBJECTIVE: The mechanism of action of anti-B cell therapy in multiple sclerosis (MS) is not fully understood. Here, we compared the effect of anti-CD20 therapy on microglial activation in two distinct focal rat models of MS. METHODS: The effect of anti-CD20 therapy on lesion formation and extralesio...
Autores principales: | Anthony, Daniel C, Dickens, Alex M, Seneca, Nicholas, Couch, Yvonne, Campbell, Sandra, Checa, Begona, Kersemans, Veerle, Warren, Edward A, Tredwell, Matthew, Sibson, Nicola R, Gouverneur, Veronique, Leppert, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241793/ https://www.ncbi.nlm.nih.gov/pubmed/25493280 http://dx.doi.org/10.1002/acn3.94 |
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