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Disruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and Complex Glycans

The carbohydrate modification of serine and threonine residues with O-linked beta- N-acetylglucosamine (O-GlcNAc) is ubiquitous and governs cellular processes ranging from cell signaling to apoptosis. The O-GlcNAc modification along with other carbohydrate modifications, including N-linked and O-lin...

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Detalles Bibliográficos
Autores principales: Ghosh, Salil K., Bond, Michelle R., Love, Dona C., Ashwell, G. Gilbert, Krause, Michael W., Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241842/
https://www.ncbi.nlm.nih.gov/pubmed/25505447
http://dx.doi.org/10.3389/fendo.2014.00197