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NF-κB-induced KIAA1199 promotes survival through EGFR signalling

Constitutive activation of EGFR- and NF-κB-dependent pathways is a hallmark of cancer, yet signalling proteins that connect both oncogenic cascades are poorly characterized. Here we define KIAA1199 as a BCL-3- and p65-dependent gene in transformed keratinocytes. KIAA1199 expression is enhanced on hu...

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Detalles Bibliográficos
Autores principales: Shostak, Kateryna, Zhang, Xin, Hubert, Pascale, Göktuna, Serkan Ismail, Jiang, Zheshen, Klevernic, Iva, Hildebrand, Julien, Roncarati, Patrick, Hennuy, Benoit, Ladang, Aurélie, Somja, Joan, Gothot, André, Close, Pierre, Delvenne, Philippe, Chariot, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241993/
https://www.ncbi.nlm.nih.gov/pubmed/25366117
http://dx.doi.org/10.1038/ncomms6232