Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter

The ATP-binding cassette (ABC) transporter associated with antigen processing (TAP) participates in immune surveillance by moving proteasomal products into the endoplasmic reticulum (ER) lumen for major histocompatibility complex class I loading and cell surface presentation to cytotoxic T cells. He...

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Detalles Bibliográficos
Autores principales: Grossmann, Nina, Vakkasoglu, Ahmet S., Hulpke, Sabine, Abele, Rupert, Gaudet, Rachelle, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242082/
https://www.ncbi.nlm.nih.gov/pubmed/25377891
http://dx.doi.org/10.1038/ncomms6419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242082/
https://www.ncbi.nlm.nih.gov/pubmed/25377891
http://dx.doi.org/10.1038/ncomms6419

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