Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis

Cellular TG stores are efficiently hydrolyzed by adipose TG lipase (ATGL). Its coactivator comparative gene identification-58 (CGI-58) strongly increases ATGL-mediated TG catabolism in cell culture experiments. To investigate the consequences of CGI-58 deficiency in murine macrophages, we generated...

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Detalles Bibliográficos
Autores principales: Goeritzer, Madeleine, Schlager, Stefanie, Radovic, Branislav, Madreiter, Corina T., Rainer, Silvia, Thomas, Gwynneth, Lord, Caleb C., Sacks, Jessica, Brown, Amanda L., Vujic, Nemanja, Obrowsky, Sascha, Sachdev, Vinay, Kolb, Dagmar, Chandak, Prakash G., Graier, Wolfgang F., Sattler, Wolfgang, Brown, J. Mark, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242449/
https://www.ncbi.nlm.nih.gov/pubmed/25316883
http://dx.doi.org/10.1194/jlr.M052613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242449/
https://www.ncbi.nlm.nih.gov/pubmed/25316883
http://dx.doi.org/10.1194/jlr.M052613

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