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Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance

Elongation of very long chain fatty acid-like family member 6 (ELOVL6) is a fatty acyl elongase that performs the initial and rate-limiting condensing reaction required for microsomal elongation of long-chain fatty acids. Our previous in vitro studies suggested that ELOVL6 elongated long-chain satur...

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Detalles Bibliográficos
Autores principales: Moon, Young-Ah, Ochoa, Courtney R., Mitsche, Matthew A., Hammer, Robert E., Horton, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242452/
https://www.ncbi.nlm.nih.gov/pubmed/25281760
http://dx.doi.org/10.1194/jlr.M054353