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Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance
Elongation of very long chain fatty acid-like family member 6 (ELOVL6) is a fatty acyl elongase that performs the initial and rate-limiting condensing reaction required for microsomal elongation of long-chain fatty acids. Our previous in vitro studies suggested that ELOVL6 elongated long-chain satur...
Autores principales: | Moon, Young-Ah, Ochoa, Courtney R., Mitsche, Matthew A., Hammer, Robert E., Horton, Jay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242452/ https://www.ncbi.nlm.nih.gov/pubmed/25281760 http://dx.doi.org/10.1194/jlr.M054353 |
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