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A DNA aptamer with high affinity and specificity for molecular recognition and targeting therapy of gastric cancer

BACKGROUND: Aptamers have emerged as excellent molecular probes for cancer diagnosis and therapy. The aim of the current study was to determine the feasibility of using DNA aptamer cy-apt 20 developed by live cell-SELEX for detecting and targeting gastric cancer. METHODS: The specificity, sensitivit...

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Detalles Bibliográficos
Autores principales: Cao, Hong-Yong, Yuan, Ai-Hua, Chen, Wei, Shi, Xue-Song, Miao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242496/
https://www.ncbi.nlm.nih.gov/pubmed/25248985
http://dx.doi.org/10.1186/1471-2407-14-699