Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming

BACKGROUND: Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylation may divide and differentiate into cancer cells. Unfortunately, little effor...

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Detalles Bibliográficos
Autores principales: Shao, Xiaojian, Zhang, Cuiyun, Sun, Ming-An, Lu, Xuemei, Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242552/
https://www.ncbi.nlm.nih.gov/pubmed/25404570
http://dx.doi.org/10.1186/1471-2164-15-978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242552/
https://www.ncbi.nlm.nih.gov/pubmed/25404570
http://dx.doi.org/10.1186/1471-2164-15-978

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