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Extracellular Mycobacterial DnaK Polarizes Macrophages to the M2-Like Phenotype

Macrophages are myeloid cells that play an essential role in inflammation and host defense, regulating immune responses and maintaining tissue homeostasis. Depending on the microenvironment, macrophages can polarize to two distinct phenotypes. The M1 phenotype is activated by IFN-γ and bacterial pro...

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Detalles Bibliográficos
Autores principales: Lopes, Rafael L., Borges, Thiago J., Araújo, Jessica F., Pinho, Nathana G., Bergamin, Letícia S., Battastini, Ana Maria O., Muraro, Stéfanie P., Souza, Ana Paula D., Zanin, Rafael F., Bonorino, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242626/
https://www.ncbi.nlm.nih.gov/pubmed/25419575
http://dx.doi.org/10.1371/journal.pone.0113441