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Extracellular Mycobacterial DnaK Polarizes Macrophages to the M2-Like Phenotype
Macrophages are myeloid cells that play an essential role in inflammation and host defense, regulating immune responses and maintaining tissue homeostasis. Depending on the microenvironment, macrophages can polarize to two distinct phenotypes. The M1 phenotype is activated by IFN-γ and bacterial pro...
Autores principales: | Lopes, Rafael L., Borges, Thiago J., Araújo, Jessica F., Pinho, Nathana G., Bergamin, Letícia S., Battastini, Ana Maria O., Muraro, Stéfanie P., Souza, Ana Paula D., Zanin, Rafael F., Bonorino, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242626/ https://www.ncbi.nlm.nih.gov/pubmed/25419575 http://dx.doi.org/10.1371/journal.pone.0113441 |
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