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Cardiac Myosin Binding Protein C Phosphorylation Affects Cross-Bridge Cycle's Elementary Steps in a Site-Specific Manner

Based on our recent finding that cardiac myosin binding protein C (cMyBP-C) phosphorylation affects muscle contractility in a site-specific manner, we further studied the force per cross-bridge and the kinetic constants of the elementary steps in the six-state cross-bridge model in cMyBP-C mutated t...

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Detalles Bibliográficos
Autores principales: Wang, Li, Sadayappan, Sakthivel, Kawai, Masakata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242647/
https://www.ncbi.nlm.nih.gov/pubmed/25420047
http://dx.doi.org/10.1371/journal.pone.0113417