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Increased tumor distribution and expression of histidine-rich plasmid polyplexes

BACKGROUND: Selecting nonviral carriers for in vivo gene delivery is often dependent on determining the optimal carriers from transfection assays in vitro. The rationale behind this in vitro strategy is to cast a net sufficiently wide to identify the few effective carriers of plasmids for in vivo st...

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Detalles Bibliográficos
Autores principales: Leng, Qixin, Chou, Szu-Ting, Scaria, Puthupparampil V, Woodle, Martin C, Mixson, A James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242722/
https://www.ncbi.nlm.nih.gov/pubmed/25303767
http://dx.doi.org/10.1002/jgm.2807