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Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown whether a similar sequential scheme applies. In thi...

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Detalles Bibliográficos
Autores principales: Bizarro, Jonathan, Charron, Christophe, Boulon, Séverine, Westman, Belinda, Pradet-Balade, Bérengère, Vandermoere, Franck, Chagot, Marie-Eve, Hallais, Marie, Ahmad, Yasmeen, Leonhardt, Heinrich, Lamond, Angus, Manival, Xavier, Branlant, Christiane, Charpentier, Bruno, Verheggen, Céline, Bertrand, Edouard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242836/
https://www.ncbi.nlm.nih.gov/pubmed/25404746
http://dx.doi.org/10.1083/jcb.201404160