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Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

Accumulation of type I collagen fibrils in tumors is associated with an increased risk of metastasis. Invadosomes are F-actin structures able to degrade the extracellular matrix. We previously found that collagen I fibrils induced the formation of peculiar linear invadosomes in an unexpected integri...

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Detalles Bibliográficos
Autores principales: Juin, Amélie, Di Martino, Julie, Leitinger, Birgit, Henriet, Elodie, Gary, Anne-Sophie, Paysan, Lisa, Bomo, Jeremy, Baffet, Georges, Gauthier-Rouvière, Cécile, Rosenbaum, Jean, Moreau, Violaine, Saltel, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242841/
https://www.ncbi.nlm.nih.gov/pubmed/25422375
http://dx.doi.org/10.1083/jcb.201404079