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Potential roles of 5´ UTR and 3´ UTR regions in post-trans-criptional regulation of mouse Oct4 gene in BMSC and P19 cells

OBJECTIVE(S): OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to ge...

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Detalles Bibliográficos
Autores principales: Ghiasvand, Saeedeh, Bakhshinejad, Babak, Mowla, Seyed Javad, Sadeghizadeh, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242918/
https://www.ncbi.nlm.nih.gov/pubmed/25429339