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Magnetization transfer ratio in the delayed-release dimethyl fumarate DEFINE study

We measured changes in brain magnetization transfer ratio (MTR) as a potential indicator of myelin density in brain tissue of patients with relapsing-remitting multiple sclerosis (RRMS) treated with delayed-release dimethyl fumarate (DMF) in the Phase 3 DEFINE study. DEFINE was a randomized, double-...

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Detalles Bibliográficos
Autores principales: Arnold, Douglas L., Gold, Ralf, Kappos, Ludwig, Bar-Or, Amit, Giovannoni, Gavin, Selmaj, Krzysztof, Yang, Minhua, Zhang, Ray, Stephan, Monica, Sheikh, Sarah I., Dawson, Katherine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242981/
https://www.ncbi.nlm.nih.gov/pubmed/25270680
http://dx.doi.org/10.1007/s00415-014-7504-7