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BIMMER: a novel algorithm for detecting differential DNA methylation regions from MBDCap-seq data

DNA methylation is a common epigenetic marker that regulates gene expression. A robust and cost-effective way for measuring whole genome methylation is Methyl-CpG binding domain-based capture followed by sequencing (MBDCap-seq). In this study, we proposed BIMMER, a Hidden Markov Model (HMM) for diff...

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Detalles Bibliográficos
Autores principales: Mao, Zijing, Ma, Chifeng, Huang, Tim H-M, Chen, Yidong, Huang, Yufei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243086/
https://www.ncbi.nlm.nih.gov/pubmed/25474268
http://dx.doi.org/10.1186/1471-2105-15-S12-S6