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BIMMER: a novel algorithm for detecting differential DNA methylation regions from MBDCap-seq data
DNA methylation is a common epigenetic marker that regulates gene expression. A robust and cost-effective way for measuring whole genome methylation is Methyl-CpG binding domain-based capture followed by sequencing (MBDCap-seq). In this study, we proposed BIMMER, a Hidden Markov Model (HMM) for diff...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243086/ https://www.ncbi.nlm.nih.gov/pubmed/25474268 http://dx.doi.org/10.1186/1471-2105-15-S12-S6 |