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Visualization of genetic disease-phenotype similarities by multiple maps t-SNE with Laplacian regularization
BACKGROUND: From a phenotypic standpoint, certain types of diseases may prove to be difficult to accurately diagnose, due to specific combinations of confounding symptoms. Referred to as phenotypic overlap, these sets of disease-related symptoms suggest shared pathophysiological mechanisms. Few atte...
Autores principales: | Xu, Weiwei, Jiang, Xingpeng, Hu, Xiaohua, Li, Guangrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243097/ https://www.ncbi.nlm.nih.gov/pubmed/25350393 http://dx.doi.org/10.1186/1755-8794-7-S2-S1 |
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