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Genomic landscape of metastatic colorectal cancer

Response to drug therapy in individual colorectal cancer (CRC) patients is associated with tumour biology. Here we describe the genomic landscape of tumour samples of a homogeneous well-annotated series of patients with metastatic CRC (mCRC) of two phase III clinical trials, CAIRO and CAIRO2. DNA co...

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Detalles Bibliográficos
Autores principales: Haan, Josien C., Labots, Mariette, Rausch, Christian, Koopman, Miriam, Tol, Jolien, Mekenkamp, Leonie J. M., van de Wiel, Mark A., Israeli, Danielle, van Essen, Hendrik F., van Grieken, Nicole C. T., Voorham, Quirinus J. M., Bosch, Linda J. W., Qu, Xueping, Kabbarah, Omar, Verheul, Henk M. W., Nagtegaal, Iris D., Punt, Cornelis J. A., Ylstra, Bauke, Meijer, Gerrit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243240/
https://www.ncbi.nlm.nih.gov/pubmed/25394515
http://dx.doi.org/10.1038/ncomms6457