The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice

Maintaining a single active X-chromosome by repressing Xist is crucial for embryonic development in mice. Although the Xist activator RNF12/RLIM is present as a maternal factor, maternal Xist (Xm-Xist) is repressed during preimplantation phases to establish imprinted X-chromosome inactivation (XCI)....

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Detalles Bibliográficos
Autores principales: Fukuda, Atsushi, Tomikawa, Junko, Miura, Takumi, Hata, Kenichiro, Nakabayashi, Kazuhiko, Eggan, Kevin, Akutsu, Hidenori, Umezawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243243/
https://www.ncbi.nlm.nih.gov/pubmed/25394724
http://dx.doi.org/10.1038/ncomms6464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243243/
https://www.ncbi.nlm.nih.gov/pubmed/25394724
http://dx.doi.org/10.1038/ncomms6464

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