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Inactivation of mammalian Ero1α is catalysed by specific protein disulfide-isomerases

Disulfide formation within the endoplasmic reticulum is a complex process requiring a disulfide exchange protein such as PDI (protein disulfide-isomerase) and a mechanism to form disulfides de novo. In mammalian cells, the major pathway for de novo disulfide formation involves the enzyme Ero1α (endo...

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Detalles Bibliográficos
Autores principales: Shepherd, Colin, Oka, Ojore B. V., Bulleid, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243250/
https://www.ncbi.nlm.nih.gov/pubmed/24758166
http://dx.doi.org/10.1042/BJ20140234