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Inactivation of mammalian Ero1α is catalysed by specific protein disulfide-isomerases
Disulfide formation within the endoplasmic reticulum is a complex process requiring a disulfide exchange protein such as PDI (protein disulfide-isomerase) and a mechanism to form disulfides de novo. In mammalian cells, the major pathway for de novo disulfide formation involves the enzyme Ero1α (endo...
Autores principales: | Shepherd, Colin, Oka, Ojore B. V., Bulleid, Neil J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243250/ https://www.ncbi.nlm.nih.gov/pubmed/24758166 http://dx.doi.org/10.1042/BJ20140234 |
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