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CNS axon regeneration inhibitors stimulate an immediate early gene response via MAP kinase-SRF signaling
BACKGROUND: CNS axon regeneration inhibitors such as Nogo and CSPGs (Chondroitin Sulfate Proteoglycans) are major extrinsic factors limiting outgrowth of severed nerve fibers. However, knowledge on intracellular signaling cascades and gene expression programs activated by these inhibitors in neurons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243276/ https://www.ncbi.nlm.nih.gov/pubmed/25406759 http://dx.doi.org/10.1186/s13041-014-0086-6 |