Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

RATIONALE: Mineral particles in the lung cause inflammation and silicosis. In myeloid and bronchial epithelial cells the inflammasome plays a role in responses to crystalline silica. Thioredoxin (TRX) and its inhibitory protein TRX-interacting protein link oxidative stress with inflammasome activati...

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Detalles Bibliográficos
Autores principales: Peeters, Paul M, Eurlings, Irene M J, Perkins, Timothy N, Wouters, Emiel F, Schins, Roel P F, Borm, Paul J A, Drommer, Wolfgang, Reynaert, Niki L, Albrecht, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243278/
https://www.ncbi.nlm.nih.gov/pubmed/25406505
http://dx.doi.org/10.1186/s12989-014-0058-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243278/
https://www.ncbi.nlm.nih.gov/pubmed/25406505
http://dx.doi.org/10.1186/s12989-014-0058-0

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