Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach

BACKGROUND: The master transactivator CIITA is essential to the regulation of Major Histocompatibility Complex (MHC) class II genes and an effective immune response. CIITA is known to modulate a small number of non-MHC genes involved in antigen presentation such as CD74 and B2M but its broader genom...

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Detalles Bibliográficos
Autores principales: Wong, Daniel, Lee, Wanseon, Humburg, Peter, Makino, Seiko, Lau, Evelyn, Naranbhai, Vivek, Fairfax, Benjamin P, Chan, Kenneth, Plant, Katharine, Knight, Julian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243378/
https://www.ncbi.nlm.nih.gov/pubmed/25366989
http://dx.doi.org/10.1186/s13059-014-0494-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243378/
https://www.ncbi.nlm.nih.gov/pubmed/25366989
http://dx.doi.org/10.1186/s13059-014-0494-z

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