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Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair

Mesenchymal stem cell (MSC) transplantation has attracted much attention in myocardial infarction therapy. One of the limitations is the poor survival of grafted cells in the ischemic microenvironment. Small interfering RNA-mediated prolyl hydroxylase domain protein 2 (PHD2) silencing in MSCs holds...

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Detalles Bibliográficos
Autores principales: Zhu, Kai, Lai, Hao, Guo, Changfa, Li, Jun, Wang, Yulin, Wang, Lingyan, Wang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243506/
https://www.ncbi.nlm.nih.gov/pubmed/25429216
http://dx.doi.org/10.2147/IJN.S71586