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Cerebellar Plasticity and Motor Learning Deficits in a Copy Number Variation Mouse Model of Autism

A common feature of autism spectrum disorder (ASD) is the impairment of motor control and learning, occurring in a majority of children with autism, consistent with perturbation in cerebellar function. Here we report alterations in motor behavior and cerebellar synaptic plasticity in a mouse model (...

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Detalles Bibliográficos
Autores principales: Piochon, Claire, Kloth, Alexander D, Grasselli, Giorgio, Titley, Heather K, Nakayama, Hisako, Hashimoto, Kouichi, Wan, Vivian, Simmons, Dana H, Eissa, Tahra, Nakatani, Jin, Cherskov, Adriana, Miyazaki, Taisuke, Watanabe, Masahiko, Takumi, Toru, Kano, Masanobu, Wang, Samuel S-H, Hansel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243533/
https://www.ncbi.nlm.nih.gov/pubmed/25418414
http://dx.doi.org/10.1038/ncomms6586