Dysregulation of antiviral helicase pathways in systemic lupus erythematosus

In the autoimmune disease systemic lupus erythematosus (SLE), our normal antiviral defenses are inappropriately activated, resulting in over-activity of the type I interferon (IFN) pathway. This increased activity of the type I IFN pathway is an important primary pathogenic factor in the disease. Em...

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Detalles Bibliográficos
Autores principales: Oliveira, Luciana, Sinicato, Nailú A., Postal, Mariana, Appenzeller, Simone, Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243696/
https://www.ncbi.nlm.nih.gov/pubmed/25505487
http://dx.doi.org/10.3389/fgene.2014.00418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243696/
https://www.ncbi.nlm.nih.gov/pubmed/25505487
http://dx.doi.org/10.3389/fgene.2014.00418

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