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Dysregulation of antiviral helicase pathways in systemic lupus erythematosus

In the autoimmune disease systemic lupus erythematosus (SLE), our normal antiviral defenses are inappropriately activated, resulting in over-activity of the type I interferon (IFN) pathway. This increased activity of the type I IFN pathway is an important primary pathogenic factor in the disease. Em...

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Detalles Bibliográficos
Autores principales:	Oliveira, Luciana, Sinicato, Nailú A., Postal, Mariana, Appenzeller, Simone, Niewold, Timothy B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243696/ https://www.ncbi.nlm.nih.gov/pubmed/25505487 http://dx.doi.org/10.3389/fgene.2014.00418

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