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iNKT/CD1d-antitumor immunotherapy significantly increases the efficacy of therapeutic CpG/peptide-based cancer vaccine

BACKGROUND: Therapeutic cancer vaccines aim to boost the natural immunity against transformed cancer cells, and a series of adjuvants and co-stimulatory molecules have been proposed to enhance the immune response against weak self-antigens expressed on cancer cells. For instance, a peptide/CpG-based...

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Detalles Bibliográficos
Autores principales: Corgnac, Stéphanie, Perret, Rachel, Zhang, Lianjun, Mach, Jean-Pierre, Romero, Pedro, Donda, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243737/
https://www.ncbi.nlm.nih.gov/pubmed/25426294
http://dx.doi.org/10.1186/s40425-014-0039-8